Nickel(0)-mediated intramolecular cyclization.
نویسندگان
چکیده
منابع مشابه
Iodine mediated intramolecular C2-amidative cyclization of indoles: a facile access to indole fused tetracycles.
A novel and metal-free I2-mediated intramolecular C2 amidation of indoles under mild reaction conditions is developed. This methodology affords various indole fused tetracyclic compounds, such as benzo[4,5]imidazo[1,2-a]indoles by intramolecular C2 amidation of N-aryl substituted indoles. This C2 sulfonamidative cyclization also offers convenient access to indolo[2,3-b]indoles and dihydroindolo...
متن کاملStudies on Lewis acid-mediated intramolecular cyclization reactions of allene-ene systems.
The Lewis acid-mediated reactions of allene-ene compounds, derived from 3-methylcitronellal or dimethyl malonate, were carried out using various Lewis acids such as ethylaluminum dichloride, diethylaluminum chloride, titanium chloride, zinc chloride etherate, or boron trifluoride etherate, affording unexpectedly intramolecular [2+2]cycloaddition products under some particular reaction condition...
متن کاملMechanistic studies on the CAN-mediated intramolecular cyclization of δ-aryl-β-dicarbonyl compounds
The synthesis of 2-tetralones through the cyclization of δ-aryl-β-dicarbonyl substrates by using CAN is described. Appropriately functionalized aromatic substrates undergo intramolecular cyclizations generating 2-tetralone derivatives in moderate to good yields. DFT computational studies indicate that successful formation of 2-tetralones from δ-aryl-β-dicarbonyl radicals is dependent on the sta...
متن کاملExcited-State Parameters of One Intramolecular Cyclization by TD-DFT, CIS and ZINDO Methods
Using a time-dependent-density functional theory (TD-DFT), Configuration Interaction Singles (CIS) and Zerner’s Intermediate Neglect of Differential Overlap (ZINDO) methods, we have investigated the UV-Visible spectra of one new intramolecular cyclization at before and after intramolecular attack. All structures were optimized at the B3LYP/6-311++G** level while UV-Visible parameters were calcul...
متن کاملIntramolecular cyclization of propargyl derivatives using environmentally friendly methodologies*
The electrochemical intramolecular cyclization of propargyl derivatives containing a carbon–halogen bond in N,N’-dimethylformamide at constant current in a diaphragmless cell has been developed using Ni(II) complexes as electron-transfer mediators.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Journal of Synthetic Organic Chemistry, Japan
سال: 1990
ISSN: 0037-9980,1883-6526
DOI: 10.5059/yukigoseikyokaishi.48.381